SOB

Sob is a verb meaning cry. Sob and SoB may refer to:
 * Souls on Board (sometimes POB for People on Board), used in Aviation communication
 * Seventeen or Bust, a distributed computing project
 * Special Operations Battalion (SOB), an elite unit of the Croatian army
 * Society of Old Brooklynites
 * Son of a bitch, an insult or curse phrase, sometimes abbreviated as "S.O.B."
 * Sons of Ben (MLS supporters association)
 * Suggested opening bid, a term in auctioneering
 * Super Oralloy Bomb, a nuclear bomb
 * Senate Office Building
 * Dirksen Senate Office Building
 * Russell Senate Office Building
 * Hart Senate Office Building
 * S.O.B. Hill, a mountain in Utah, United States
 * Start of business, the start of the business day (as opposed to EOB)

Biomedicine

 * Shortness of breath or dyspnea, a medical symptom relating to breathing difficulties
 * Sobralia, a genus of orchids
 * Super optimal broth, a bacterial growth medium

Music and media

 * S.O.B. (film), a 1981 film by Blake Edwards
 * The Sob, a 1953 Turkish film
 * S.O.B. (band), a Japanese grindcore band
 * "S.O.B." (song), by Nathaniel Rateliff and the Night Sweats, 2015
 * Scars on Broadway, an American rock band
 * Sons of Batman, a group of characters in a Batman comics miniseries
 * Sons of Butcher (band), a Canadian rock band
 * Sons of Butcher (TV show), a cartoon inspired by the band
 * Sounds of Blackness, an American vocal and instrumental ensemble
 * SOB's, Sounds of Brazil, a live music venue in New York City
 * Styles of Beyond, an underground rap group
 * Switched-On Bach, an album by Walter Carlos
 * S.O.B.s, an episode of the television series Arrested Development

Transport

 * Seaford-Oyster Bay Expressway
 * Balaton Airport, SOB in IATA code
 * South Bend station (Amtrak), SOB is its station code
 * Southbourne railway station, SOB in Network Rail code
 * Stadt-Omnibus Bern, a former public transport operator in Bern, Switzerland
 * Südostbahn, a railway company in Switzerland
 * SüdostBayernBahn, a railway company in southern Germany
 * MS Spirit of Britain, a Dover - Calais P&O Ferry

Toponyms

 * Sob (river), a river in Siberia, a tributary of the Ob
 * Sob River, a river in Ukraine, a tributary of Southern Bug