SPLA

SPLA may refer to:


 * Sahrawi People's Liberation Army, the army of the Sahrawi Arab Democratic Republic, previously the armed branch of the Polisario Front
 * Socialist Propaganda League of America, former group within the ranks of the Socialist Party of America, 1915–1919
 * South Sudan People's Defense Forces, formerly Sudan People's Liberation Army
 * SPLA-Nasir and SPLA-United, a Sudanese breakaway faction formed in 1991
 * Services Provider License Agreement, created by Microsoft to allow service providers to host software services for their customers
 * SHARE Program Library Agency, a repository of contributed programs for IBM computers.