SPSE

SPSE can refer to:
 * Société du pipeline sud-européen, operator of a crude oil pipeline in France, Switzerland and Germany
 * Society of Photographic Scientists and Engineers, a former name for the Society for Imaging Science and Technology (IS&T)
 * Society of Professionals, Scientists and Engineers, union representing some University of California staff at the Lawrence Livermore National Laboratory
 * South Pacific Stock Exchange, a stock exchange based in Suva, Fiji
 * Southern Pump Services Engineering, pump manufacturer in Perivale, United Kingdom
 * Syndicat du personnel de soutien en éducation, labour union that forms part of the Centrale des syndicats du Québec in Canada
 * Sistem Pengadaan Secara Elektronik, a nationwide Electronic Government Procurement System of Government of Indonesia
 * Stowarzyszenie Pasjonatów Sportów Elektronicznych, Polska organizacja pozarządowa, działająca w obszarze e-sportu.
 * SharePoint Server Subscription Edition, a Microsoft collaboration product.