SSSI (disambiguation)

SSSI can mean:
 * Solid state storage initiative, a network promoting the use of solid state storage
 * Site of Special Scientific Interest, a UK nature conservation designation
 * Site of Special Scientific Interest (Hong Kong), a Hong Kong nature conservation designation
 * Skin and skin structure infection, a bacterial infection of the skin
 * Stainless Steel Studios, a video games company
 * "Special Secret Song Inside", a track from the Red Hot Chili Peppers album The Uplift Mofo Party Plan
 * Surveying and Spatial Sciences Institute