Sacrifice of Isaac (disambiguation)

The Sacrifice of Isaac refers to the Binding of Isaac, a story from the Hebrew Bible found in Genesis 22.

The Sacrifice of Isaac may also refer to:
 * Sacrifice of Isaac (Andrea del Sarto), three paintings of c. 1527–1530 by Andrea del Sarto
 * Abraham and Isaac (Titian), a painting of c. 1543–1544 by Titian, also called the Sacrifice of Isaac
 * Sacrifice of Isaac (Caravaggio), two paintings of c. 1598–1603 by Caravaggio
 * The Sacrifice of Isaac (Rembrandt), a painting of 1635 by Rembrandt
 * Abraham's Sacrifice of Isaac (Bencovich), a painting of 1715 by Federico Bencovich