Safo

Safo may refer to:


 * Balcha Safo (1863–1936), Ethiopian general
 * Lucy Safo, Ghanaian writer
 * Safo, Mali, a town and commune in the Koulikoro Region of Mali
 * Safo, Niger, a village and rural commune in Niger
 * Safo, historia de una pasión, a 1943 Argentine romantic drama film
 * Sarah Adwoa Safo, a Ghanaian lawyer and politician
 * Safo'63, ("Love and Sex (Sappho '63)"), a 1964 Mexican film