Saint Serena

Saint Serena may be:


 * Serena of Rome - (3rd century), legendary figure, erroneously believed to be the wife of Diocletian, celebrated on August 16
 * Serena of Spoleto - (4th century), martyr in Spoleto, celebrated on December 7


 * Geography


 * Santa Serena, toponym in the town of Schizzanello in the Roma Capitale.