Samuel Klein

Samuel Klein may refer to:
 * Samuel Klein (businessman) (1923–2014), founder of the Casas Bahia chain of stores in Brazil
 * Samuel Klein (doctor), doctor and nutritional expert based at Washington University
 * Samuel Klein (scholar) (1886–1940), historian and geography researcher of the Land of Israel
 * Samuel Klein (1886–1942), founder of S. Klein department stores
 * Sam Klein (soccer), Australian footballer
 * Sam Klein, lead character in the Allan Levine series by the same name