Samuel Mills

Samuel Mills may refer to:
 * Samuel Sylvester Mills (1806–1874), Canadian businessman and member of the Senate of Canada
 * Samuel John Mills (1783–1818), American preacher who helped found the American Bible Society and the American Colonization Society
 * Samuel Mills (footballer) (1871–?), English footballer
 * Samuel C. Mills (1833–1911), produced the earliest surviving photographic record of the Oregon Trail and California Trail
 * Samuel Meyers Mills Jr. (1842–1907), United States Army officer
 * Samuel Atta Mills (born 1956), Ghanaian politician
 * Samuel Mills, early settler after whom Millswood, South Australia is named