Samuel Osborne

Samuel or Sam Osborne or Osborn may refer to:


 * Samuel Osborne (custodian) (1833–1903), African American custodian and caretaker at Colby College
 * Samuel W. Osborne (1868–1952), Australian newspaper founder and editor
 * Sam Osborne (footballer) (born 1999), English footballer
 * Sam Osborne (racing driver) (born 1993), British racing driver
 * Samuel Osborn (surgeon) (1848–1936), British surgeon
 * Samuel Osborn & Company, a steelmaker and engineering tool manufacturer in Sheffield, South Yorkshire