Samuel Spencer

Samuel Spencer may refer to:


 * Samuel Spencer (North Carolina politician) (1734–1794), North Carolina judge, lawyer, and Revolutionary War colonel
 * Samuel M. Spencer (1875–1960), politician on Hawaii island
 * Samuel R. Spencer (1871–1961), American politician, lieutenant governor of Connecticut
 * Samuel Spencer (railroad executive) (1847–1906), first president of the Southern Railway
 * S. B. Spencer (1827–1901), mayor of Atlanta, Georgia
 * Sam Spencer (1902–1987), English footballer
 * Samuel Reid Spencer Jr. (1919–2013), president of Davidson College
 * Samuel A. Spencer, American politician in the Virginia House of Delegates
 * Samuel Spencer (DC commissioner) (1910–1997), president of the District of Columbia Board of Commissioners