Sandra Clark (disambiguation)

Sandra E. Clark is an American diplomat.

Sandra Clark may also refer to:
 * Sandra Clark (British actress), Scottish actress who featured in the TV series The Mackinnons (1977) and Me and My Girl (1985–1988)
 * Sandra Clark (American actress), American actress known for her role in the film Scream for Help (1984)
 * Sandra Clark, a fictional character on the TV series 227