Santa Fe High School

Santa Fe High School may refer to:


 * Santa Fe High School (California), in Santa Fe Springs, California, U.S.
 * Santa Fe High School (Florida), in Alachua, Florida, U.S.
 * Santa Fe High School (New Mexico), in Santa Fe, New Mexico, U.S.
 * Santa Fe High School (Texas), in the Santa Fe Independent School District, Santa Fe, Texas, U.S.
 * 2018 Santa Fe High School shooting
 * Santa Fe Independent School District
 * Edmond Santa Fe High School, in Edmond, Oklahoma, U.S.