Santa Fe Trail (disambiguation)

Santa Fe Trail is a historic 19th century transportation route.

Santa Fe Trail may also refer to:
 * Santa Fe National Historic Trail, National Historic Trail through Missouri, Kansas, Oklahoma, Colorado, and New Mexico, USA
 * Santa Fe Trail Scenic and Historic Byway, National Scenic Byway in Colorado, USA
 * Santa Fe Trail Scenic Byway, National Scenic Byway in New Mexico, USA
 * Santa Fe Trail (film), a 1940 American Western film
 * Santa Fe Trail (short subjects) a 1943–1945 Warner Bros short subjects Western series with Robert Shayne
 * Santa Fe Trails, the local transit authority in Santa Fe, New Mexico
 * The Santa Fe Trail (1923 film), a 1923 Western film serial
 * The Santa Fe Trail (1930 film), a 1930 American pre-Code western film
 * New Santa Fe Trail, an auto trail
 * Santa Fe Trail problem, genetic programming exercise