Santa Helena

Santa Helena may refer to:


 * Helena of Constantinople, the mother of Emperor Constantine the Great
 * Saint Helena, an island in the South Atlantic Ocean
 * Santa Helena de Goiás, a municipality in Brazil
 * Santa Helena de Minas, a municipality in Brazil
 * Santa Helena, Paraná, a municipality in Brazil
 * Santa Helena, Santa Catarina, a municipality in Brazil
 * Santa Helena, Maranhão, a municipality in Brazil
 * Santa Helena del Opón, a town and municipality in Colombia
 * Grupo Santa Helena, a group of painters
 * Santa Helena Esporte Clube, a Brazilian football (soccer) club