Santiago District

Santiago District may refer to:
 * Santiago District, Palmares, Alajuela Province, Costa Rica
 * Santiago District, San Ramón, Alajuela Province, Costa Rica
 * Santiago District, Puriscal, San José Province, Costa Rica
 * Santiago District, San Rafael, Heredia Province, Costa Rica
 * Santiago District, Paraíso, Cartago Province, Costa Rica
 * Santiago District, Veraguas, Panama
 * Santiago District, Paraguay, Misiones Department
 * Santiago District, Cusco, Peru
 * Santiago District, Ica, Peru