Santo Domingo Cathedral

Santo Domingo Cathedral may refer to:
 * Basilica Cathedral of Santa María la Menor, Santo Domingo, Dominican Republic
 * Episcopal Cathedral of the Epiphany-Union Church of Santo Domingo, Dominican Republic
 * Cathedral of the Roman Catholic Diocese of Santo Domingo in Ecuador
 * Cobán Cathedral (Catedral de Santo Domingo de Guzmán), Guatemala
 * Basco Cathedral, Philippines, also known as Santo Domingo
 * Bayombong Cathedral (Santo Domingo de Guzman Cathedral), Nueva Vizcaya, Philippines
 * Santo Domingo de la Calzada Cathedral, Spain