Sayle

Sayle may refer to:
 * Alexei Sayle (born 1952), English stand-up comedian, actor, author and former recording artist
 * Amy Sayle (1884–1970), British politician and health visitor
 * Charles Edward Sayle (1864–1924), English Uranian poet, literary scholar and librarian
 * Darrius Sayle, major character in Snakehead
 * Desiree Sayle, Deputy Assistant to the President and Director of the USA Freedom Corps for the Bush Administration
 * Jeff Sayle (motorcyclist) (born 1954), former Grand Prix motorcycle road racer from Australia
 * Jeff Sayle (rugby union) (1942–2019), Australian rugby union international
 * Murray Sayle OAM (1926–2010), Australian journalist, novelist and adventurer
 * Robert Sayle, founder of a department store located in Cambridge
 * William Sayle (1590–1671), prominent British landholder who was Governor of Bermuda in 1643 and again in 1658