Scruff

Scruff may refer to:


 * Scruff (anatomy), a loose, non-sensitive area of skin by which a mother can carry her young
 * Scruff (app), a mobile application for gay men
 * Scruff (TV series), a Spanish children's animated television series
 * Scruff Connors (1952–2016), Canadian radio broadcaster
 * Mr. Scruff (born 1972), British DJ and artist