Sean Byrne

Sean Byrne may refer to:

Footballers

 * Sean Byrne (Irish footballer) (fl. 1920s and 1930s), Irish soccer player
 * Sean Byrne (New Zealand footballer) (1955–2003), New Zealand international football player

Others

 * Sean Byrne (filmmaker), Australian filmmaker
 * Sean Byrne (politician) (born 1937), Irish Fianna Fáil politician, TD 1982–1987, Senator 1989–1997
 * John "Sean" Byrne (1946–2008), Irish-born American musician