Sean Smith

Sean Smith may refer to:


 * Sean Smith (defensive tackle) (born 1965), American football player
 * Sean Smith (defensive end) (born 1967), former American football player for the New England Patriots
 * Sean Smith (skier) (born 1971), American Olympic skier
 * Sean Smith (diplomat) (1978–2012), who died in the 2012 attack on the U.S. consulate in Benghazi
 * Sean Smith (cornerback) (born 1987), American football cornerback
 * Sean Smith (chemist), academic and director of NCI Australia
 * Sean Smith (photojournalist), British photographer and filmmaker
 * Sean Smith, Lord Harrower, Scottish judge
 * Sean Smith (English singer), (born 1985), member of British pop duo Same Difference
 * Sean Smith (Welsh singer), member of Welsh band The Blackout
 * Sean Smith, alias for voice actor Sean Schemmel
 * Sean Smith (Brookside), a character from the British television series Brookside