Sec61 alpha 1

Protein transport protein Sec61 subunit alpha isoform 1 is a protein encoded by the SEC61A1 gene in humans.

The protein encoded by this gene belongs to the SecY/Sec61α family. It plays a crucial role in the insertion of secretory and membrane polypeptides into the endoplasmic reticulum. This protein is found to be tightly associated with membrane-bound ribosomes, either directly or through adaptor proteins. This gene encodes an alpha subunit of the heteromeric SEC61 complex, which contains beta and gamma subunits.