Second City

Second City or The Second City may refer to:
 * Second city of the United Kingdom
 * Chicago, nicknamed the Second City
 * The Second City, an improvisational comedy troupe initially based in Chicago
 * Mercenary: The Second City, a 1986 expansion pack for the video game Mercenary
 * "Second City", an episode of 2007 Canadian/American TV series The Dresden Files
 * Second City derby, Association-football rivalry between Aston Villa and Birmingham City
 * Secondcity, stage name of American-born British musician Rowan Harrington (born 1987)