Second government of Fernando López Miras

The second government of Fernando López Miras was formed on 1 August 2019, following the latter's election as President of the Region of Murcia by the Regional Assembly of Murcia on 26 July and his swearing-in on 29 July, as a result of the People's Party (PP) allying itself with Citizens (Cs) and mustering the external support from Vox in exchange for policy compromises following the 2019 Murcian regional election. It succeeded the first López Miras government and has been the incumbent government of the Region of Murcia since 1 August 2019, a total of days, or 4 years, 11 months, 4 days.

Until March 2021, the cabinet comprised members of the PP and Cs as well as a number of independents, to become the first coalition government to be formed in the region. From that point onwards, the government has been formed by the PP and a number of expelled members from both Cs and Vox.

Cabinet changes
López Miras's second government saw a number of cabinet changes during its tenure:


 * On 20 January 2021, López Miras announced the resignation of his health minister, Manuel Villegas, after a scandal broke out over the latter's unduly receiving a dose of the COVID-19 vaccine, skipping the legally-established vaccination protocols and procedures. He was replaced in the post on 23 January by Juan José Pedreño.
 * On 18 February 2021, transparency, participation and public administration minister Beatriz Ballesteros announced her resignation citing the "loss of confidence" from the new regional leadership of the party that proposed her, Cs. The resignation was effective from 20 February. Ballesteros was replaced in her post by José Gabriel Sánchez Torregrosa on 23 February.
 * On 10 March 2021, both the Spanish Socialist Workers' Party (PSOE) and Cs announced an agreement under which they would jointly bring down the PP governments in the city and the region of Murcia. In response, López Miras expelled Ana Martínez Vidal and José Gabriel Sánchez Torregrosa, as members from Cs's regional leadership, but preserved two of the party's members in the government in hopes of securing their support to thwart the no-confidence motion. On 12 March, López Miras and Isabel Franco announced an agreement whereby three out of the six Cs deputies in the region—Franco, María del Valle Miguélez and Francisco Álvarez García—would back the government in exchange for minister positions, which were formalized the next day. In response, Cs expelled all its four remaining members in the government from the party.
 * On 3 April 2021, López Miras secured the parliamentary support of several rebel Vox deputies by appointing María Isabel Campuzano as new Education and Culture minister, in a government reorganization that also saw mayor of Yecla Marcos Ortuño being elected to the new Presidency, Tourism and Sports portfolio and Javier Celdrán's powers being restructured into the Economy, Finance and Digital Administration ministry.
 * On 7 April 2021, Francisco Álvarez García announced his resignation as minister of Employment, Research and Universities, in order to take over the control of the Citizens's parliamentary group in the Regional Assembly of Murcia, with his portfolio being merged with that of Business and Industry minister and Spokesperson María del Valle Miguélez.
 * On 18 November 2021, the Transparency, Participation and Public Administration portfolio was reorganized into the Transparency, Security and Emergencies ministry.
 * On 8 February 2022, as a result of a government crisis caused by Education minister María Isabel Campuzano over her dismissal of Institute of Cultural and Arts Industries director-general, José Ramón Palazón (a trusted person of one of the Vox expelled deputies that maintained their support to the López Miras government), her portfolio was stripped of its Culture competences, which were transferred and merged into the new Presidency, Tourism, Culture and Sports ministry.
 * On 11 May 2022, the Minister of Transparency, Security and Emergencies, Antonio Sánchez Lorente, resigned from his post because of personal health reasons. As a result, this Ministry was disestablished and its competences transferred to the restructured Ministries of Women, Equality, LGTBI, Families, Social Policy and Transparency (led by Isabel Franco) and Water, Agriculture, Livestock, Fisheries, Environment and Emergencies (led by Antonio Luengo).

Council of Government
The Council of Government is structured into the offices for the president of the Region of Murcia, the vice president and a number of ministries (10 from August 2019 to April 2021, 9 from April 2021 to May 2022 and 8 from May 2022).

{| class="wikitable" ! Portfolio ! Name ! width="100px" colspan="2"| Party ! width="125px"| Took office ! width="125px"| Left office ! Ref. ! colspan="7"|
 * colspan="7" bgcolor="#F2F2F2" align="center"| ← López Miras II Government → (1 August 2019 – present)
 * colspan="7" bgcolor="#F2F2F2" align="center"| ← López Miras II Government → (1 August 2019 – present)
 * President
 * Fernando López Miras
 * width="1" style="background-color:;"|
 * PP
 * 29 July 2019
 * Incumbent
 * align="center"|
 * align="center"|
 * Vice President Minister of Women, Equality, LGTBI, Families and Social Policy
 * Isabel Franco
 * style="background-color:;"|
 * Cs / Ind.
 * 1 August 2019
 * 13 May 2022
 * align="center"|
 * Minister of the Presidency and Finance
 * Javier Celdrán
 * style="background-color:;"|
 * PP
 * 1 August 2019
 * 3 April 2021
 * align="center"|
 * Minister of Business, Industry and Spokesperson
 * Ana Martínez Vidal
 * style="background-color:;"|
 * Cs
 * 1 August 2019
 * 10 March 2021
 * align="center"|
 * Minister of Tourism, Youth and Sports
 * María Cristina Sánchez
 * style="background-color:;"|
 * PP
 * 1 August 2019
 * 3 April 2021
 * align="center"|
 * Minister of Education and Culture
 * Esperanza Moreno
 * style="background-color:;"|
 * PP
 * 1 August 2019
 * 3 April 2021
 * align="center"|
 * Minister of Water, Agriculture, Livestock, Fisheries and Environment
 * Antonio Luengo
 * style="background-color:;"|
 * PP
 * 1 August 2019
 * 13 May 2022
 * align="center"|
 * Minister of Transparency, Participation and Public Administration
 * Beatriz Ballesteros
 * style="background-color:;"|
 * Cs (Ind.)
 * 1 August 2019
 * 20 February 2021
 * align="center"|
 * Minister of Development and Infrastructures
 * José Ramón Díez de Revenga
 * style="background-color:;"|
 * PP
 * 1 August 2019
 * Incumbent
 * align="center"|
 * Minister of Health
 * Manuel Villegas
 * style="background-color:;"|
 * PP (Ind.)
 * 1 August 2019
 * 23 January 2021
 * align="center"|
 * Minister of Employment, Research and Universities
 * Miguel Motas
 * style="background-color:;"|
 * Cs (Ind.)
 * 1 August 2019
 * 13 March 2021
 * align="center"|
 * colspan="7"|
 * align="center"|
 * Minister of Employment, Research and Universities
 * Miguel Motas
 * style="background-color:;"|
 * Cs (Ind.)
 * 1 August 2019
 * 13 March 2021
 * align="center"|
 * colspan="7"|
 * colspan="7"|
 * colspan="7"|

Changes January 2021
! Portfolio ! Name ! colspan="2"| Party ! Took office ! Left office ! Ref.
 * Minister of Health
 * Juan José Pedreño
 * style="background-color:;"|
 * PP (Ind.)
 * 23 January 2021
 * Incumbent
 * align="center"|
 * colspan="7"|
 * colspan="7"|
 * colspan="7"|

Changes February 2021
! Portfolio ! Name ! colspan="2"| Party ! Took office ! Left office ! Ref.
 * Minister of Transparency, Participation and Public Administration
 * José Gabriel Sánchez Torregrosa
 * style="background-color:;"|
 * Cs
 * 23 February 2021
 * 10 March 2021
 * align="center"|
 * colspan="7"|
 * colspan="7"|
 * colspan="7"|

Changes March 2021
! Portfolio ! Name ! colspan="2"| Party ! Took office ! Left office ! Ref.
 * rowspan="2"| Minister of Business, Industry and Spokesperson
 * colspan="6"| Javier Celdrán took on the office's attributions from 10 to 13 March 2021.
 * María del Valle Miguélez
 * style="background-color:;"|
 * Cs / Ind.
 * 13 March 2021
 * 9 April 2021
 * align="center"|
 * rowspan="2"| Minister of Transparency, Participation and Public Administration
 * colspan="6"| Isabel Franco took on the office's attributions from 10 to 13 March 2021.
 * Antonio Sánchez Lorente
 * style="background-color:;"|
 * Cs / Ind.
 * 13 March 2021
 * 18 November 2021
 * align="center"|
 * Minister of Employment, Research and Universities
 * Francisco Álvarez García
 * style="background-color:;"|
 * Cs / Ind.
 * 13 March 2021
 * 8 April 2021
 * align="center"|
 * colspan="7"|
 * Cs / Ind.
 * 13 March 2021
 * 8 April 2021
 * align="center"|
 * colspan="7"|
 * colspan="7"|

Changes April 2021
! Portfolio ! Name ! colspan="2"| Party ! Took office ! Left office ! Ref.
 * Minister of the Presidency, Tourism and Sports
 * Marcos Ortuño
 * style="background-color:;"|
 * PP
 * 3 April 2021
 * 8 February 2022
 * align="center"|
 * Minister of Economy, Finance and Digital Administration
 * Javier Celdrán
 * style="background-color:;"|
 * PP
 * 3 April 2021
 * Incumbent
 * align="center"|
 * Minister of Business, Employment, Universities and Spokesperson
 * María del Valle Miguélez
 * style="background-color:;"|
 * Independent
 * 9 April 2021
 * Incumbent
 * align="center"|
 * Minister of Education and Culture
 * María Isabel Campuzano
 * style="background-color:;"|
 * Independent
 * 3 April 2021
 * 8 February 2022
 * align="center"|
 * rowspan="2"|
 * colspan="6"| María del Valle Miguélez took on the office's attributions from 8 to 9 April 2021.
 * colspan="6"| Disestablished on 9 April 2021.
 * colspan="7"|
 * rowspan="2"|
 * colspan="6"| María del Valle Miguélez took on the office's attributions from 8 to 9 April 2021.
 * colspan="6"| Disestablished on 9 April 2021.
 * colspan="7"|
 * colspan="6"| Disestablished on 9 April 2021.
 * colspan="7"|
 * colspan="7"|

Changes November 2021
! Portfolio ! Name ! colspan="2"| Party ! Took office ! Left office ! Ref.
 * Minister of Transparency, Security and Emergencies
 * Antonio Sánchez Lorente
 * style="background-color:;"|
 * Independent
 * 18 November 2021
 * 12 May 2022
 * align="center"|
 * colspan="7"|
 * colspan="7"|
 * colspan="7"|

Changes February 2022
! Portfolio ! Name ! colspan="2"| Party ! Took office ! Left office ! Ref.
 * Minister of the Presidency, Tourism, Culture and Sports
 * Marcos Ortuño
 * style="background-color:;"|
 * PP
 * 8 February 2022
 * Incumbent
 * align="center"|
 * Minister of Education
 * María Isabel Campuzano
 * style="background-color:;"|
 * Independent
 * 8 February 2022
 * Incumbent
 * align="center"|
 * colspan="7"|
 * align="center"|
 * colspan="7"|
 * colspan="7"|

Changes May 2022
! Portfolio ! Name ! colspan="2"| Party ! Took office ! Left office ! Ref.
 * Vice President Minister of Women, Equality, LGTBI, Families, Social Policy and Transparency
 * Isabel Franco
 * style="background-color:;"|
 * Independent
 * 13 May 2022
 * Incumbent
 * align="center"|
 * Minister of Water, Agriculture, Livestock, Fisheries, Environment and Emergencies
 * Antonio Luengo
 * style="background-color:;"|
 * PP
 * 13 May 2022
 * Incumbent
 * align="center"|
 * colspan="6"| Disestablished on 13 May 2022.
 * }
 * colspan="6"| Disestablished on 13 May 2022.
 * }
 * colspan="6"| Disestablished on 13 May 2022.
 * }