Sepe (surname)

Sepe is an Italian surname. Notable people with the surname include:


 * Angelo Sepe, (1941–1984) Italian-American gangster
 * Crescenzio Sepe, Italian cardinal
 * Daniele Sepe, Italian musician
 * Frank Sepe, American fitness author
 * Luigi Sepe, Italian footballer
 * Majda Sepe, (1937–2006) Slovenian singer
 * Michele Sepe, Italian rugby player
 * Mimmo Sepe (died 2020), Italian comedian