Sergio Santos

Sergio Santos may refer to:
 * Sergio Santos (baseball) (born 1983), American baseball player
 * Sérgio Santos (volleyball) (born 1975), also known as Serginho or Escadinha, Brazilian volleyball player
 * Sergio Santos (footballer, born 1994), Brazilian football forward for FC Cincinnati
 * Sérgio Santos (footballer, born 1998), Portuguese football forward for Portimonense
 * Sergio Santos (footballer, born 2001), Spanish football right-back for Real Madrid