Serious Business

Serious Business may refer to


 * Serious Business (Johnny Winter album), 1985
 * Serious Business (Third World album), 1989
 * "Serious Business", a song from the album Uh-huh by John Cougar Mellencamp and the B-side of "Pink Houses"
 * Serious Business, one of the earliest game developers on Facebook, acquired by Zynga in 2010
 * Serious Business Records, a record label founded by Travis Harrison and Andy Ross