Shupe

Shupe may refer to:
 * Shupe, Virginia, U.S.
 * Shupe Peak, Victoria Land, Antarctica

People with the surname

 * Anson Shupe, American sociologist
 * Bryan Shupe, American politician
 * Ryan Shupe, American musician
 * Vince Shupe (1921–1962), Major League Baseball first baseman
 * Glen Shupe, an Irish drug addict at HBO drama Oz