Sicario

may refer to:


 * Sicario (1994 film), a Venezuelan drama film by Joseph Novoa
 * Sicario (2015 film), an American crime film by Denis Villeneuve
 * Sicario: Day of the Soldado (2018; titled Sicario 2: Soldado in the UK), an American crime film by Stefano Sollima, sequel to Villeneuve's 2015 film
 * Sicario (album), a 2005 thrash/death metal album by Criminal