Simplicius

Simplicius may refer to:


 * Persons
 * Pope Simplicius (d. 483 AD)
 * Simplicius of Cilicia (d. c. 560 AD), philosopher
 * Saint Simplicius, legendary 'founding' bishop of the Sardinian Diocese of Civita
 * Simplicius, Constantius and Victorinus (fl. 2nd century), Roman martyrs and saints
 * Simplicius, Faustinus and Beatrix (d. 302 or 303 AD), Roman martyrs and saints


 * Art and fiction
 * Simplicius Simplicissimus, a picaresque novel about the character of the same name
 * Simplicius (operetta), an operetta by Johann Strauss II
 * A character in Dialogue Concerning the Two Chief World Systems, a 1632 work by Galileo