Sirio (disambiguation)

Sirio is a low-floor tram built by Ansaldobreda

Sirio may also refer to:


 * Sirio (album), 2022 album by Lazza
 * Sirio Carrapa (born 1952), Italian mystic
 * Sirio Maccioni (1932–2020), restaurateur and author based in New York City
 * MV Sirio, a Maltese and Panamanian train ferry
 * SS Sirio, an Italian immigrant transporter ship, wrecked off Cartagena in 1906
 * Sirio, a brand of engines by Italian American Motor Engineering