Siskiyou

Siskiyou may refer to:
 * Siskiyou Mountains, a mountain range in northern California and southern Oregon
 * Siskiyou National Forest, in Oregon and California
 * Siskiyou County, California
 * Siskiyou Trail, an old Native American and pioneer trail connecting Oregon and California
 * Siskiyou Summit, a mountain pass (4,037 ft) on Interstate 5 in southern Oregon
 * Siskiyou Mountains salamander
 * Siskiyou (newspaper), a student-run newspaper at Southern Oregon University in Ashland, Oregon.
 * Siskiyou (band), a Canadian indie folk band.