Sixteen Mile Creek

Sixteen Mile Creek or Sixteenmile Creek may refer to:

Canada

 * Ontario
 * Sixteen Mile Creek (Halton Region), which flows to the northwest shore of Lake Ontario
 * Sixteen Mile Creek (Muskoka District), a tributary of the Boyne River
 * Sixteen Mile Creek (Niagara Region), which flows to the southwest shore of Lake Ontario
 * Sixteenmile Creek (Ontario), in Elgin County, which flows into Lake Erie

United States

 * Sixteenmile Creek (Florida), a tributary of the St. Johns River
 * Sixteen Mile Creek (Montana), a tributary of the Missouri River
 * Sixteenmile Creek (Ohio), which flows into Lake Erie