Slaughter Branch

Slaughter Branch is a stream in northern Franklin County in the U.S. state of Missouri. It is a tributary to Brushy Creek.

The headwaters of the stream are at 38.51722°N, -91.17278°W and the confluence with Brushy Creek is at 38.51722°N, -91.11833°W. The source area for the stream lies just south of Campbellton and Missouri Route 185.

Slaughter Branch most likely derives its name from George Slaughterback, a pioneer citizen.