Solvent Yellow 7

Solvent Yellow 7 is an aromatic organic molecule and a common azo dye with a formula of C6H5N2C6H4OH. It has a phenolic hydroxyl and an azo group in the same molecule.

Synthesis
Like most azobenzenes, Solvent Yellow 7 can be synthesized by the reaction of the phenyldiazonium salt with phenol. The optimal pH value for this azo coupling is 8.5-10. The reaction is carried out in water, since sodium chloride (or potassium chloride) formed in the reaction is soluble in water, while the product precipitates.

As azo dyes are not usually water soluble, the effect of various solvents on them has been studied analytically, and likewise analytical methods and calculations for the color concentration developed.

Further reactions
The molecule can be further reacted including with bromine, and other halogens. Other reactions include nitration. The reactivity with Grignard reagents has also been studied.

Toxicology
The toxicology has been extensively studied, including IARC studies. There have been other extensive reviews.

External Websites

 * Santa Cruz Biotechnology Safety Data Sheet