St. Francis de Sales Catholic Church (Paducah, Kentucky)

The St. Francis DeSales Roman Catholic Church (Church of St. Francis de Sales) is a historic church building at 116 S. 6th Street in Paducah, Kentucky. It was built in 1899 and, together with its 1927-built rectory, was added to the National Register of Historic Places in 1979.

It is a Classical Revival-style building named for St. Francis de Sales.