St. Louis-San Francisco Railroad Depot (Poplar Bluff, Missouri)

St. Louis-San Francisco Railroad Depot is a historic train station located at Poplar Bluff, Butler County, Missouri. The station was built in 1928 by the St. Louis–San Francisco Railway. It is a one-story, Mission Revival style brick building sheathed in textured stucco. It sits on a concrete foundation, has a gable and hipped Spanish tile roof, and features two interior brick and stucco chimneys. The building is presently occupied as a railroad museum.

It was added to the National Register of Historic Places in 1994.