Succinate-semialdehyde dehydrogenase (NADP+)

Succinate-semialdehyde dehydrogenase (NADP+) (, succinic semialdehyde dehydrogenase (NADP+), succinyl semialdehyde dehydrogenase (NADP+), succinate semialdehyde:NADP+ oxidoreductase, NADP-dependent succinate-semialdehyde dehydrogenase, GabD) is an enzyme with systematic name succinate-semialdehyde:NADP+ oxidoreductase. This enzyme catalyses the following chemical reaction


 * succinate semialdehyde + NADP+ + H2O $$\rightleftharpoons$$ succinate + NADPH + 2 H+

This enzyme participates in the degradation of glutamate and 4-aminobutyrate.