Succinate-semialdehyde dehydrogenase (acylating)

Succinate-semialdehyde dehydrogenase (acylating) (, succinyl-coA reductase, coenzyme-A-dependent succinate-semialdehyde dehydrogenase) is an enzyme with systematic name succinate semialdehyde:NADP+ oxidoreductase (CoA-acylating). This enzyme catalyses the following chemical reaction


 * succinate semialdehyde + CoA + NADP+ $$\rightleftharpoons$$ succinyl-CoA + NADPH + H+

Catalyses the NADPH-dependent reduction of succinyl-CoA to succinate semialdehyde.