Sweet Lou

Sweet Lou may refer to:


 * Sweet Lou (album), a 1974 album by jazz saxophonist Lou Donaldson
 * Sweet Lou (horse) (foaled 2009)

People with the nickname

 * Lou Hudson (1944–2014), former All-Star basketball player
 * Louis Dunbar (born 1953), basketball player for the Harlem Globetrotters
 * Lou Johnson (1934–2020), Major League Baseball player
 * Lou Piniella (born 1943), Major League Baseball manager and player
 * Lou Williams (born 1986), NBA basketball player
 * Lou Whitaker (born 1957), Major League Baseball player
 * Lou Singer, a main character in the 2003 movie Grind