Sweetwater Creek

Sweetwater Creek may refer to:
 * Sweetwater Creek (novel), a novel by Anne Rivers Siddons
 * Sweetwater Creek, Florida, an unincorporated community in Hillsborough County, Florida
 * Sweetwater Creek (Chattahoochee River), Georgia
 * Sweetwater Creek State Park, in Douglas County, Georgia
 * Sweetwater Creek (Echeconnee Creek tributary), Georgia
 * Sweetwater Creek (Flint River tributary), Georgia
 * Sweetwater Creek (Logan Creek), a stream in Missouri
 * Sweetwater Creek (Comanche County, Texas)
 * Sweetwater Creek (Gray County, Texas)
 * Sweetwater Creek (Nolan County, Texas), namesake of Sweetwater, Texas
 * Sweetwater Creek (Tennessee River), tributary to the Tennessee River at Loudon, Tennessee
 * Sweetwater Creek in Frankston, Victoria, Australia