Swimming at the 2019 African Games – Men's 4 × 100 metre medley relay

The Men's 4 × 100 metre medley relay competition of the 2019 African Games was held on 24 August 2019.

Records
Prior to the competition, the existing world and championship records were as follows.

The following new records were set during this competition.

Final
The final was started on 24 August.