Swimming at the 2022 Mediterranean Games – Men's 4 × 100 metre medley relay

The men's 4 × 100 metre medley relay competition at the 2022 Mediterranean Games was held on 4 July 2022 at the Aquatic Center of the Olympic Complex in Bir El Djir.

Records
Prior to this competition, the existing world and Mediterranean Games records were as follows:

Heats
The heats were started at 10:55.

Final
The final was held at 19:10.