Swimming at the 2022 Mediterranean Games – Women's 4 × 100 metre freestyle relay

The women's 4 × 100 metre freestyle relay competition at the 2022 Mediterranean Games was held on 5 July 2022 at the Aquatic Center of the Olympic Complex in Bir El Djir.

Records
Prior to this competition, the existing world and Mediterranean Games records were as follows:

The following records were established during the competition:

Results
The final was held at 19:34.