Swimming at the 2022 Mediterranean Games – Women's 4 × 100 metre medley relay

The women's 4 × 100-metre medley relay competition at the 2022 Mediterranean Games was held on 4 July 2022 at the Aquatic Center of the Olympic Complex in Bir El Djir.

Records
Prior to this competition, the existing world and Mediterranean Games records were as follows:

Results
The final was held at 18:53.