Swimming at the 2022 World Aquatics Championships – Women's 400 metre individual medley

The Women's 400 metre individual medley competition at the 2022 World Aquatics Championships was held on 25 June 2022.

Records
Prior to the competition, the existing world and championship records were as follows.

Heats
The heats were started at 09:00.

Final
The final was held at 19:01.