Swimming at the 2023 Pan American Games – Mixed 4 × 100 metre medley relay

The mixed 4 × 100 metre medley relay competition of the swimming events at the 2023 Pan American Games were held on October 23, 2023, at the Aquatic Center in Santiago, Chile.

Records
Prior to this competition, the existing world and Pan American Games records were as follows:

Heats
The highest eight scores advance to the final.

Final
The final was held on October 23.