Syringetin

Syringetin is an O-methylated flavonol, a type of flavonoid. It is found in red grape (absent in white grape), in Lysimachia congestiflora and in Vaccinium uliginosum (bog billberries). It is one of the phenolic compounds present in wine.

It induces human osteoblast differentiation through bone morphogenetic protein-2/extracellular signal-regulated kinase 1/2 pathway.

Metabolism
Syringetin is formed from laricitrin by the action of the enzyme laricitrin 5′-O-methyltransferase (myricetin O-methyltransferase).

Glycosides

 * Syringetin-3-O-galactoside
 * Syringetin-3-O-glucoside
 * Syringetin 3-rhamnoside (CAS number 93126-00-2)
 * Syringetin-3-O-rutinoside found in Larix sibirica
 * Syringetin 3-O-(6′′-acetyl)-β-glucopyranoside found in Picea abies (Norway spruce)