TGIF

TGIF may refer to:

Arts and media

 * TGIF (TV programming block), a former two-hour programming block on the American television network ABC
 * "TGIF" (song), a song by GloRilla
 * "Last Friday Night (T.G.I.F.)", a 2011 single by Katy Perry
 * "T.G.I.F. (Thank God I'm Fresh)", a song by Kid Cudi from Man on the Moon: The End of Day
 * "T.G.I.F.", a song by Lonestar from Let's Be Us Again
 * "TGIF", a song by K.Flay from Inside Voices / Outside Voices
 * "TGIF", a song by Le Tigre from Feminist Sweepstakes

Science and technology

 * Tgif (program), an interactive 2-D drawing tool under X11 for Unix and the file format it uses, .tgif
 * Tactical Ground Intercept Facility, a US Military Intelligence collection platform
 * Transforming growth interacting factor
 * TGIF1, a protein that in humans is encoded by the TGIF1 gene
 * TGIF2, a protein that in humans is encoded by the TGIF2 gene

Other uses

 * Thank God It's Friday (disambiguation)
 * T.G.I. Friday's, an American restaurant chain