TME

TME may refer to:


 * TME (operating system), Transaction Machine Environment, former ICL computer operating system
 * TME (psychedelics), drugs
 * Transmisogyny exempt
 * Tencent Music Entertainment Group, music distribution company
 * Total mesorectal excision, removal of cancerous bowel tissue
 * Toyota Motor Europe
 * Transmissible mink encephalopathy
 * Trimethylolethane, a triol, an organic compound
 * Tumor microenvironment
 * Tickle Me Elmo